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Patriciah Karuru
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Biopharmaceutics Pharmacokinetics Brahmankar Pdf 126


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Biopharmaceutics Pharmacokinetics Brahmankar Pdf 126


Biopharmaceutics and Pharmacokinetics: A Treatise by D. M. Brahmankar


Biopharmaceutics and Pharmacokinetics: A Treatise is a book by D. M. Brahmankar that covers the principles and applications of biopharmaceutics and pharmacokinetics in drug development, evaluation, and therapy. The book was published by Vallabh Prakashan in 2005 and has 285 pages.


The book aims to provide a comprehensive and systematic treatment of the concepts and methods of biopharmaceutics and pharmacokinetics, with emphasis on the practical aspects and problem-solving skills. The book covers topics such as drug absorption, distribution, metabolism, excretion, bioavailability, bioequivalence, pharmacokinetic models, pharmacokinetic parameters, pharmacokinetic variability, pharmacodynamic relationships, dose-response relationships, dosing regimen design, and pharmacokinetic-pharmacodynamic modeling.


The book is intended for students, teachers, researchers, and practitioners of pharmacy, pharmaceutical sciences, pharmacology, clinical pharmacology, medicine, and related disciplines. The book is also useful for professionals involved in drug discovery, development, regulation, and marketing.


The book is available in PDF format online at https://www.scribd.com/document/329195113/BHRAMANKAR-Biopharmaceutics. The PDF file has 410 pages and a size of 126 MB.


The book is based on the author's extensive teaching and research experience in the field of biopharmaceutics and pharmacokinetics. The author is a professor of pharmaceutics at Bharati Vidyapeeth College of Pharmacy in Pune, India. He has authored several books and papers on biopharmaceutics and pharmacokinetics and has received several awards and honors for his contributions to the field.


The book is a valuable resource for anyone interested in learning more about the science and art of biopharmaceutics and pharmacokinetics.


The book also introduces the concept of physiologically based pharmacokinetic (PBPK) modeling and simulation, which is a powerful tool for predicting drug absorption and disposition in various physiological and pathological conditions. PBPK modeling and simulation can help to optimize drug product design, reduce animal testing, support clinical trial design, and facilitate regulatory decision making. The book provides examples of PBPK applications in drug product development and evaluation.


The book is organized into four parts: Part I covers the basic principles of biopharmaceutics and pharmacokinetics, including drug dissolution, absorption, distribution, metabolism, excretion, and pharmacokinetic models. Part II deals with the applications of biopharmaceutics and pharmacokinetics in drug product development and evaluation, such as bioavailability, bioequivalence, in vitro-in vivo correlation, biowaiver, and biopharmaceutics classification system. Part III focuses on the applications of biopharmaceutics and pharmacokinetics in clinical pharmacology and therapeutics, such as pharmacokinetic variability, pharmacodynamic relationships, dose-response relationships, dosing regimen design, and pharmacokinetic-pharmacodynamic modeling. Part IV introduces the concept and applications of PBPK modeling and simulation in drug product development and evaluation.


The book is well-written, clear, concise, and comprehensive. It contains numerous figures, tables, examples, exercises, case studies, and references to facilitate learning and understanding. The book also includes appendices that provide useful information on mathematical methods, physiological parameters, pharmacokinetic software, and regulatory guidances. ec8f644aee






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